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Furthermore, the protein disulfide isomerase (PDI) directly interacts with integrins, mediating disulfide-thiol exchange, resulting in conformational changes and activation (Popierlarski et al

Society of Thoracic Radiology, 2009

While everyone's body responds differently, the synergistic effects are well-documented

Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration