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Macrophage-elicited loss of estrogen receptor-alpha in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus

Patients will be offered multiple follow-up outpatient appointments with the various specialities that were involved during their inpatient management particularly dermatology and ophthalmology

The implications of germline variants for lung cancer therapy and familial genetic screening are largely unexplored

We used 50 ng of cDNA for the PCR template, real-time PCR was conducted using thermal cycler Quant Studio 3 (Thermo Fisher Scientific, Waltham, MA, USA) and thermal cycling conditions were: 2 min at 50C and 10 min at 95C followed by 40 cycles at 9C for 15 s and at 60C for 1 min (37)