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The contents they carry vary depending on the cell's life cycle and biological state ( In recent studies, it has been found that human infection with Mycobacterium tuberculosis (Mtb) results in the presence of EVs in the blood and secretions that carry Mtb fragments, specific proteins, and other substances, and there is hope that the contents within them can be used as biomarkers of tuberculosis or targets for drug guidance ( The contents of EVs are highly complex, and extracting valuable biomarkers for the diagnosis and treatment of renal tuberculosis from them has been a significant challenge in recent research

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9,1113 DPN induces progressive sensory fiber degeneration and neuropathic pain, mediated by voltage-gated sodium channel (VGSC