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Furthermore, the number of true seronegative patients may be very low due to a simple inability of currently available screening tests to detect levels of some antibodies (Meriggioli 2012a)

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Abstract Pulmonary hypertension (PH) is a clinical syndrome characterized by progressive elevation of pulmonary vascular resistance, whose pathological process is closely related to the crosstalk between immune dysregulation and metabolic remodeling, forming a complex immune-metabolic regulatory network