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Biol Trace Elem Res (2021) 200:31715

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Since in vivo and in vitro studies are inconsistent, broader and more detailed studies focused on the mechanisms responsible for oxidative stress modulation under metformin intervention are still needed ( 4.2 In vivo studies In a study by Javadipour et al., a rat model of arsenic-induced diabetes was treated with metformin (dose: 300 mg/kg)

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