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Iron imbalance in adipose tissue influences glucose metabolism by affecting adipocyte differentiation, tissue growth, adipokine secretion, lipid synthesis, and lipolysis [54]

Additionally, IgA nephropathy, constituting a primary etiology with CKD progression potential, demonstrates elevated Escherichia coli abundance in affected patients relative to healthy controls, while altered Enterococcaceae , Moraxella , and Acinetobacter populations associate with renal dysfunction (Li X.-J