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This damage, termed oxidative stress, accumulates over time and is thought to contribute to both disease pathology and the aging process

Therefore, targeting the metabolic vulnerabilities of these cells might selectively eradicate them and improve the overall survival of patients with AML

Farahzadi R, Sanaat Z, Movassaghpour-Akbari AA, Fathi E, Montazersaheb S

Competitive experiments revealed that the addition of urea significantly weakened the drug effect, confirming that the targeting molecule was indeed UreI and providing direct evidence for drug-channel lock-and-key delivery