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doi: 10.1164/rccm.201202-0351OC

Many patients combine B12 injections with other treatments at The Pur Health

For its part, the administration of melatonin to aged Wistar rats caused a decrease in sirtuin 2 and FOXO3a expression (which were found increased in these animals, probably in an attempt to counteract harmful effects of aging), as well as a reduction in oxidative stress parameters and pro-apoptotic proteins