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Overall, ferroptosis acts as a triggering factor of inflammation, affecting the bodys immune regulatory system, promoting iron ion-induced lipid peroxidation, and inducing osteoclast differentiation while inhibiting osteoblast proliferation, leading to cartilage destruction and bone erosion

Cells 8(8):80 Kuo TC, Chen CK, Hua KT et al (2016) Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells

Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y

MARCH5-dependent NLRP3 ubiquitination is required for mitochondrial NLRP3-NEK7 complex formation and NLRP3 inflammasome activation