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and H.T.)

For example, when investigating the hypothesis that gap junctions transport toxic metabolites to neighboring cells and support their killing during APAP and thioacetamide hepatotoxicity, the fact that the new gap junction inhibitor 2-aminoethoxydipenyl-borate (2APB) protected against the injury appeared to support the hypothesis [154]

Subsequent loss of function studies showed that the ability of dietary MR to increase energy expenditure (EE), reduce fat deposition, and remodel white adipose tissue was dependent on FGF21 6