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In older adults, oxybutynin is associated with increased risk of central nervous system adverse effects, including confusion and cognitive impairment, warranting caution in patients with dementia or other geriatric vulnerabilities

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Vitamin B6 and vitamin B12 contribute to a normal homocysteine metabolism, which is essential for the maintenance of healthy blood vessels

Bax, a pro-apoptotic Bcl-2 family protein, resides in the cytoplasm and translocates to the mitochondria in response to apoptotic stimuli, where it facilitates the release of Cyt C (Shalini et al., 2015)