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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Aringhieri S., Carli M., Kolachalam S., Verdesca V., Cini E., Rossi M., McCormick P.J., Corsini G.U., Maggio R., Scarselli M

Nonetheless, these mice harbored activated mucosal immune components as demonstrated by increased numbers of lamina propria CD4(+)lymphocytes, redistribution of CD11c(+)cells, increased production of the proinflammatory cytokines interferon- and tumor necrosis factor- (TNF-), and expression of epithelial major histocompatibility complex class-I

We designate these states as intermediate and fully active for reasons described below

Nature 2014;510:412-6