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Exploring the use of dimethyl fumarate as microglia modulator for neurodegenerative diseases treatment

doi: 10.1016/j.phymed.2024.155722 121 DengJWangESJenkinsRWLiSDriesRYatesKet al

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The increased amount of GABA then downregulates the GABA receptors, making the net effect less of an inhibitory signal.[ref] GABA can also be metabolized into creatine, and an increase in both GABA and creatine is found in people with dysfunction in the ALDH5A1 gene

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