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The antigen-binding agent is often a small molecule (peptide) or an antibody or antibody fragment that binds to a disease-related antigen

Notably, incubating peripheral whole blood cultures with vitamin B12 resulted in the normalization of CCL11 expression, the increase of the neuroprotective HGF and the decrease CSF2 and CXCL10 mRNA levels in leukocytes from individuals with persistent VCD (Fig