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Although the number of CD4 + and CD8 + T cells in the peripheral blood was reduced, the number of Th17 cells was elevated, and CD8 + T cells were highly cytotoxic, suggesting that a cytokine storm may accelerate tissue destruction (Wan et al., 2020)

JAMA 291 , 29472958 (2004)

PZQ alone cannot capably reverse pathological sequelae of schistosomiasis [19], and new therapies against schistosomiasis should focus also on this problem in addition to anthelmintic performance