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Description

In general, the sensitivity of cancer cells to ferroptosis is dependent on the state of cellular metabolisms, such as the metabolisms of lipid, iron, lactate, and amino acid

JAMA 311, 563

Subsequently, H 2 O 2 can undergo decomposition into O 2 and H 2 O through the catalytic action of CAT or react with GSH in the presence of GPx, resulting in the formation of oxidized glutathione (GSSG) and water