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received support from an American Society of Hematology (ASH) Research Training Award for Fellows, an ASH Scholar Award, Clinical Scholars Biomedical Research Training Program (T32 CA009512) and a grant from the NCI (K08CA259453)

Matsuda and coworkers [45] demonstrated a considerable reduction in serum free carnitine concentration in five patients with hyperammonaemia associated with VPA therapy (of whom three had a Reye-like syndrome)

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