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471 Similarly, in a randomized controlled trial in 3,144 non-cardioembolic stroke or TIA patients, low-dose colchicine (0.5 mg daily) did not reduce risks of stroke, heart attack, or unstable angina episodes during median follow-up of 33.6 months

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Despite reports indicating the critical role of lysosomal lipase in M2 activation [43], lysosomal lipase inhibition with Lalistat1 did not demonstrate any noticeable effect (Fig