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The study by Verbruggen and colleagues investigated its potential effects on erosive hand OA (40 mg adalimumab or placebo) (249)

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Nevertheless, South Asian populations display a heterogeneous frequencies of LP (Figure 4), and European LCT/MCM6 allele 13910*T(rs4988235) , varying from 0 to ~48% with Northwestern Indians from traditional dairy herding communities have high LP, in contrast to numerous, mostly lactose intolerant, southern/eastern non-pastoral populations (89)