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Gastroenterology 127:764776 Martell M, Esteban JI, Quer J, Genesca J, Weiner A, Esteban R et al (1992) Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

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As a result, peripheral cytokines may be able to enter the CNS, where they may cause or exacerbate neuroinflammation [49]

Notably, the important regulators of lysosomal biogenesis such as TFE3 and TFEB, accompanied with key lysosomal enzymes, also showed an increased expression (Fig