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Previously, LDLR was thought to be a major source of risk for cardiovascular diseases such as atherosclerosis, but recent studies have shown that LDLR is involved in cancer signaling and malignant progression, including that of colorectal, prostate, lung, and breast cancers [199]

398 In vitro and in vivo studies indicate that indole-3-acetic acid produced by the respiratory microbiome reduces emphysema and reduces lung function through IL-22-mediated macrophage-epithelial cell interactions

Circulating MOTS-c declines with age and tracks with insulin resistance, making it both a potential longevity biomarker and a therapeutic target

Recent approaches in nanotoxicity assessment for drug delivery applications: Challenges and prospects