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The anti-diabetic actions of semaglutide include stimulation of insulin secretion, inhibition of glucagon secretion after meals and delay of gastric emptying [8]

60,64 These diverse stimuli are thought to activate NLRP3 via inducing different cellular events, including K + efflux, Ca2 + signaling, mitochondrial and lysosomal damages that release substances such as reactive oxygen species, oxidized mitochondrial DNA and lysosomal proteases

Rogler, G

Research published in the National Institutes of Health library describes how certain peptides act as anti-inflammatory agents in inflammation-related conditions, which is one reason this category has drawn so much clinical interest