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Treatmentemergent adverse events (AEs) were coded to system organ class and preferred term using the Medical Dictionary for Regulatory Activities (MedDRA) version 26.1

Targeting USP13-mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in non-small cell lung cancer

The oxygen intake in Control-B (no oxygen) was very low and can be considered negligible (data not shown)

The induction of HMOX1 has been reported for many clinically used drugs, including commonly prescribed NSAIDs, hypolipidemic, anti-aggregation drugs, H2 antihistamines, and some antihypertensive medications, as well as natural substances used as nutraceuticals [109,110]