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In preclinical models, aerobic exercise and vitamin D supplementation have been shown to improve lipid metabolism and insulin resistance in T2DM models by modulating hepatic miR-33 expression (100, 101).We separate well-supported processes, namely ROS production at Complex I and III and stress-kinase signaling, from provisional mechanisms such as in-vivo RET amplification and miR-29 or miR-141 regulation of PGC-1

Mar 2021;36(2):263-270

This indicates that macrophage-based drug delivery does not compromise, and may even enhance, the chemosensitizing effect of NFX to OXA in vitro

Valori CF, Ning K, Wyles M, et al