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A Benzophenanthridine Alkaloid, Chelerythrine Induces Apoptosis In Vitro in a Dalton's Lymphoma

Journal of Biological Chemistry, 268 (4), 25712576

Both of these mechanisms for lowering the activation energy have been observed in peptidyl prolyl isomerases (PPIases), which are naturally occurring enzymes that catalyze the cis-trans isomerization of X-Pro peptide bonds