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Dermatological side effects include rash on the skin, itching, hives, skin redness, blisters, pale skin, peeling and swelling with or without fever

We sincerely thank the reviewers for their valuable feedback and insightful suggestions, which have greatly contributed to improving the quality of this manuscript

However, pharmacokinetic studies have shown methylcobalamin stays longer in brain and liver tissues

We believe our proposed methodology is consistent with sections 1847A(i)(5) of the Act, which sets forth the payment amount that is used to determine whether coinsurance should be adjusted, and section 1847A(i)(3)(A) of the Act, which sets forth the specified amount used to determine rebate amounts