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Research has identified over 4,000 human genes that GHK-Cu modulates, with 1,584 of those being upregulated (repair/growth genes) and 747 being downregulated (inflammatory/damage genes)

doi: 10.1016/j.scitotenv.2023.161899 43 ChristoforidouE

They promote tumor progression, fuel metastasis, and protect cancer cells from apoptosis (programmed cell death) induced by high ROS or, chemotherapy and radiotherapy

Functional and PROM-related trajectories did not differ by sex overall, but women with SS-RF had lower mood at baseline, and had a higher residual headache burden over 12 months