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In contrast, RIPK3 kinase inhibitor GSK872 44 , ferroptosis inhibitor Fer-1 45 , pyroptosis inhibitor disulfiram 46 and MLKL inhibitor GW806742X 47 had no impact on TNF/CHX-induced cell death in HK2-deficient cells (Supplementary Fig

Our data demonstrate that GSTP1/P2 contribute to the finely tuned activation levels of proliferation signaling pathways and to the downstream expression of cell cycle regulators in order to achieve the proper proliferation rate of hepatocytes and the cell cycle synchrony during liver regeneration

PMID: 7565367