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The mucus matrix is primarily formed by mucin glycoproteins, characterized by repetitive domains enriched in proline-threonine-serine (P-T-S) motifs that serve as principal sites for O-linked glycosylation and form the common biophysical structure of mucins, such as Muc2 54,55

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Moreover, the mediators released by ferroptotic cells promote DC cells maturation and the effector T cells may eradicate tumor cells by inducing tumor ferroptosis[174]

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