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As we chart this terrain, it is expected to transform the post-stroke milieu from a metabolic battleground (site of competing metabolic adaptations) into a scaffold where amino acids may orchestrate metabolic repair by modulating both glycolytic flux (e.g., serine-driven one-carbon metabolism) and lipid peroxidation (e.g., cysteine-dependent glutathione synthesis), though combinatorial targeting studies are needed [186, 206]