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The use of single bacterial strain to rescue behavioral deficits associated with ASD therefore remains uncertain

Specifically, it is suggested that the positively charged interior of the nose repels ionic zinc (Zn 2+ ) such that ionic zinc delivered by throat lozenges and migrating from the mouth to the nose are more effective against rhinovirus infection than those directly delivered into the nose (119)

However, the GH response may attenuate with continuous daily use (tachyphylaxis), which is why titration strategies and periodic breaks are often incorporated [4][7]

However, many of the studies are small and have methodological flaws, which makes it difficult to give firm guidance on this supplement or confirm its effects