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Limitations include the small sample size, late treatment, lack of blinding, potential overlap of treatment effect with SOC, clinical significance of biomarker results, and limited adverse event reporting

edited and revised manuscript

The cell size, as well as intracellular sodium concentration increased

Furthermore, pathological -syn spreads between neurons via a prion-like mechanism, inducing the misfolding of normal -syn proteins, thereby accelerating degenerative changes in dopaminergic neurons (Liu et al., 2022)