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10.1007/s00018-016-2194-1 23 CardosoB

Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase

These include reduced gonadotropin secretion due to impaired positive estrogen feedback on luteinizing hormone (LH) secretion in women (21), increased adrenal androgen secretion (22), and direct blockade of gonadotropin action at the gonadal level (23, 24)