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Thus, the greater understanding of the molecular regulatory network involved in the regulation of Zn deficiency response and Zn homeostasis would contribute to Zn phyto-availability by developing crops with an increased content of bioavailable Zn in plants, which has been considered as most cost-effective methods for combating Zn deficiency in plants and malnutrition problem in humans

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*Correspondence: Jana Frahm, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers