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Neurodegenerative diseases are characterized by progressive neuron losses in specific brain regions that impact cognitive, sensory, and motor functioning

doi: 10.1073/pnas.2109256118 21 DuanS.LiH.WangF.LiL.FanH.MaY.et al

Murakami and Kudo, 2002

At the AMY 3 R, the RAMP3/CTR interface for the Cagri-bound AMY 3 R appears to be weaker than the rAmy-AMY 3 R where Y37 rAmy forms a H-bond interaction with E74 RAMP3 that stabilises the position of the ECD and the interface between the RAMP3 and CTR ECDs