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The lysolipid structure within LPLs confers hydrophilicity and versatility, which facilitates their many tissue specific functions [40]

Even lower IC 50 s (higher sensitivity) have been reported using rat primary osteoblasts (IC 50 of 2 M for cadmium) [49], which may reflect species-specific effects as well as improved responsiveness of primary cells

However, intense evidences suggest that lipid peroxidation can be the common feature that initiates and propagates the cell death