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And normal conditions dont apply to many POTS patients: Gastroparesis (delayed stomach emptying) is present in up to 40% of POTS patients, slowing fluid absorption significantly Nausea and GI dysfunction make it physically difficult to drink the volumes needed Frequent urination many POTS patients report that their bodies seem to dump fluids almost as fast as they drink them, particularly if the fluid is plain water without adequate sodium Heat exposure, exercise, and menstrual cycles all increase fluid requirements beyond what oral intake can match This is why so many POTS patients describe a frustrating pattern: they drink and drink and drink, yet their symptoms dont improve proportionally

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Matama T, Araujo R, Preto A, Cavaco-Paulo A, Gomes AC