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This is an active and beginning area of investigation, and the implications for human disease remain speculative pending controlled clinical trials

In patients with SLF by either FIB-4 or LSM we found lower absolute values of left atrium reservoir strain (indirect marker of reduced compliance) (p=0.027 and p=0.021, respectively), lower values of left atrium conduit strain (indirect marker of impaired passive emptying) (p=0.020 and p=0.0003) and lower values of right atrium reservoir strain (p=0.011 and p=0.007)

Months six through nine: peak shedding and early recovery For most patients, shedding peaks around months four through seven and then gradually diminishes

The numbers of cells were counted under an inverted microscope