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In vitamin D-deficient PCOS phenotypes, repletion improves adiponectin/leptin ratios and lowers circulating TNF- and IL-6, reflecting stabilization of the adipokine-microbiota-insulin axis (234)

Simultaneously, levels of reverse T3 (rT3)an inactive isomer of T3may rise, by activation of DIO3, further reducing the pool of biologically active thyroid hormone

Zhang F, Qian L, Flood PM

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