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A recent study by Peng et al

Both medications are trusted and effective, but they arent identical

Above all, due to their design for sustained drug release, the long-term biocompatibility of both the nanocarrier and its degradation byproducts must be established through the currently lacking chronic toxicity studies

For GHK-Cu, where the cosmetic mechanism depends on copper ion delivery to fibroblast integrins that trigger TGF- signaling and collagen gene expression, that localized dermal concentration is the only variable that matters