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IC50 was 34.19 M, 61.53 M in the senescent fibroblasts from keloid and normal skin, and 93.77 M, 104.6 M in non-senescent control fibroblasts from keloid and normal skin, respectively

However, they shouldnt be used too often, as long-term use may weaken tissues

This metabolic transition can manifest as fatigue, especially in the first few weeks of treatment

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