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However, rec-ECM1 therapy did not reverse the collagen accumulation (Fig

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain treg cell activation and suppression of antitumor immunity

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2.5.3 Necroptosis Necroptosis is a programmed cell death process dependent on the receptor-interacting serine/threonine-protein kinase 1/receptor-interacting serine/threonine-protein kinase 3/mixed lineage kinase domain-like pseudokinase (RIPK1/RIPK3/MLKL) axis