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doi: 10.3390/nu8020090

Studies indicate that poor sleep quality can negatively affect antioxidant defenses, including glutathione

Hepatology 57 , 555565 (2013)

After a further two weeks, if there is no clinical response, measurement of peak concentration 12 h after dose should be considered, and should this be less than 200 ng/ml, the dose may be increased until the concentration reaches 400 ng/ml