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The vast majority of compounds show a reduced or even complete loss of the therapeutic effect under hypoxic conditions

It is well known for its antioxidant activity, as well as, its chemopreventive, anti-inflammatory, and antiviral properties.(1) Insufficient selenium levels have been associated with several human diseases such as diabetes or cancer

Epithelial tight junction is a critical intestinal barrier, and its disruption could leak toxic substances from the gut into blood circulation and cause systemic injury