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Empagliflozin has been shown to have a cardio-protective effect on the combined risk of hospitalization for heart failure and cardiovascular death in subjects with HFpEF, an effect that is, independent of the presence of diabetes

That distinction matters for AOD-9604 because published studies have examined pathway signals, receptor context, and peptide fragment behavior in specific models [4] [5] [6]

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Heijtz et al., 2011