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According to a prior study, PD patients were observed with much greater levels of 8-OHdG in peripheral blood leukocytes than those of the healthy controls, and this difference was connected with the severity of PD (Chen et al., 2009)

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A systematic review on synthetic drugs and phytopharmaceuticals used to manage diabetes

However, GSH-S-transferase A4-4 knockdown could augment 4-HNE cytotoxicity, and its overexpression could obviously inhibit 4-HNE-induced death of chondrocytes [84]