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Fibroblast growth factor 1 (FGFR1) modulation regulates repair capacity of oligodendrocyte progenitor cells following chronic demyelination

Given that impaired autophagy and dysregulated mucin secretion are key contributors to barrier dysfunction, TB-500s regenerative and anti-inflammatory actions may indirectly support mucin2 production and mucus layer integrity, though direct evidence in colitis models remains limited