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Description

Missing a milestone does not necessarily indicate treatment failure but suggests the need for protocol review

The researchers therefore urge caution for patients with melanoma when taking any antioxidant supplements that could contain larger doses than recommended by health organisations

Life-threatening acute adverse cutaneous drug reactions

In one subject on daily furosemide therapy, the dose was increased after wk 2 of the dosing period and the previously borderline renal insufficiency worsened slightly (creatinine rose from 119 mol/L to 159 mol/L)