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however, the pathophysiology of T2DM involves insulin resistance and hyperinsulinemia

When vitamin C and linezolid were administered concomitantly, liver and kidney functions parameters were alleviated and measured values approached control levels (75.06 2.074 IU/L, 51.31 0.85 IU/L, and 71.67 4.855 IU/L for AST, ALT, and ALP levels and 3.5 0.039 mg/dL, 0.65 0.034 mg/dL, and 43.19 2.195 mg/dL for albumin, urea, and creatinine levels, respectively) compared to the LZD-treated group (p 0.05)

Besides, the other sources of endogenous ROS include the protoplasm (NADPH oxidases, hemoglobin, riboflavin), the endoplasmic reticulum (Cytochromes P450 and b5), the peroxisomes (oxidases, flavoproteins), and lysosomes (myeloperoxidase, metal ions) [32]