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Other likely effects of high iodine intake in susceptible individuals are an increased production of thyroid-infiltrating T helper 17 cells, inhibition of T regulatory cell development and an abnormal expression of TNF-related apoptosis-inducing ligand in thyrocytes, resulting in apoptosis and tissue destruction ( Reference Duntas 28 )

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The production of thrombin is triggered by the exposure of tissue factors in the arterial wall, which in turn sets off the clotting cascade

The reaction incubated for 15 min and 6 l of 50 mM DTNB was added to each well